The long and winding road of acute normovolemic hemodilution

Hemodynamic compensation during acute normovolemic hemodilution.

To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...

the long and winding road

Hemodynamic Compensation during Acute Normovolemic Hemodilution

To the Editor:—Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration. The primary compensatory mechanism during ANH is an increase in cardiac output to maintain systemic oxygen delivery. Therefore, the lower limit of an acceptable hemoglobin concentration is related to how low hemoglobin can be reduced without jeopardizin...

Acute Normovolemic Hemodilution: A Practical Approach

Justifications: Perioperative allogeneic blood transfusion can be reduced or even completely avoided by using a set of different strategies: meticulous hemostasis, the use of pharmaceutical agents that assist in the process of coagulation/ fibrinolysis, the use of blood substitutes, induced hypotension, preoperative autologous blood donation, collection and reinfusion of autologous blood during...

The Long and Winding Road

Day by day the competition get tougher, the exams harder and the textbooks larger. Indeed, it is a long and winding road for the high school graduate seeking university admission to study medicine. The graduate desiring to excel must prepare to travel a tortuous path laden with obstacles. In Iran, in order to obtain admission to medical school, one must place approximately among 3622 of the 442...